AICAR (50mg)

AICAR 50mg

AICAR (5-Aminoimidazole-4-carboxamide ribonucleotide)  a..a. “Exercise in a Bottle”

AICAR is an experimental metabolic compound that activates AMP-activated protein kinase (AMPK), a key enzyme responsible for regulating cellular energy metabolism. Often described in research as an exercise mimetic, AICAR has attracted interest for its potential effects on energy utilization, fat metabolism, glucose uptake, and physical endurance.

Key Research Areas

• AMPK activation: Stimulates a major cellular energy-sensing pathway involved in metabolic regulation.
• Fat metabolism: Research suggests increased fatty acid oxidation, potentially supporting the body's use of fat as an energy source.
• Glucose utilization: Influences glucose uptake and utilization, particularly in skeletal muscle.
• Mitochondrial function: Has been studied for its potential to promote mitochondrial adaptations associated with energy production.
• Exercise endurance: Animal studies have demonstrated improvements in endurance-related performance, contributing to its reputation as an exercise mimetic.
• Metabolic regulation: Investigated for its effects on insulin sensitivity, lipid metabolism, and cellular energy balance.

How It Works

AICAR enters cells and is converted into ZMP, which mimics AMP and activates AMPK. This triggers cellular pathways involved in increasing energy production and shifting metabolism toward energy utilization rather than energy storage.

Research Summary

AICAR is particularly interesting in metabolic and performance research because of its potential influence on fat oxidation, glucose metabolism, mitochondrial activity, and endurance-related pathways. It is frequently studied as a tool for understanding how AMPK activation influences cellular energy regulation.

50mg Vial 
For research use only